Murray and Martina Hingis beat defending champions Watson and Kontinen 6-4 6-4 as Murray sealed his second grand slam title in mixed, 10 years after winning his first here with Jelena Jankovic.
It is also 20 years since Martina Hingis edged past Jana Novotna to win her singles title on Centre Court, and the Swiss now has six major mixed doubles triumphs to add to her 12 in women's doubles and five in singles.
MARTINA HINGIS AND JAMIE MURRAY WIN
For Guernsey-born Watson, meanwhile, this was another strong run with Finland's Kontinen, backing up her progress to the third round of the singles last week where she was beaten in three sets by Victoria Azarenka.
Jamie Murray and Martina Hingis share the winners' cheque of £100,000 while Watson and Kontinen split the £50,000 runners-up prize.
After Andy Murray and Johanna Konta's exits from the singles, Watson and Jamie Murray were able to deliver two British finalists on Centre Court, even if not the pair that many home fans had wished for.
The crowd's support was certainly evenly spread, to the extent that one particularly generous spectator felt compelled to shout out, "Come on, all of you", much to the amusement of the masses.